Amifostine

 

Molecular formula: C5H15N2O3PS

 

 

Standard: USP 34

 

Assay: 99.0%

 

Characters: white or slight yellow crystalline powder.

 

Package: 25kg fiber drum

 

Storage: Stored in a well-closed container, protected from light.

 

Function: Amifostine is used therapeutically to reduce the incidence of neutropenia-related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents (e.g. cyclophosphamide) and platinum-containing agents (e.g. cisplatin). It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancer.